ISTA grew out of a series of annual international symposia first held in Germany in 1988, focusing on the development of custom prostheses for arthroplasty. The society was formally incorporated in Switzerland in 1990 as the International Society for the Study of Custom Prostheses (ISSCP) following the meeting in Nice. As the society’s horizon expanded to encompass a broader range of interests, the name was changed to ISTA in 1994. It is composed of surgeons, basic scientists, engineers, and representatives of industry, and its purpose is to promote interdisciplinary advances in the science and technology of joint replacement. ISTA sponsors an annual symposium designed to foster an exchange of information and cooperation in research efforts on an international level. It is governed by a board of directors with world wide, multi-disciplinary representation.